The maximum plasma concentration of 150 ng / ml is reached 1.5 hours after administration of 8 mg of acrivastine. The half-life of approximately 1.5 hours.Cumulation acrivastine was observed even after multiple dose over 6 days. Acrivastine practically it does not penetrate the blood-brain barrier. 87% acrivastine excreted in the urine mainly unchanged within 3 days after taking the drug, the remaining 13% of the dose excreted in the feces.
- nasal allergy winstrol results
- hay fever (hay fever)
- chronic idiopathic urticaria
- cholinergic urticaria
- cold urticaria
- pruritic atopic eczema
- hypersensitivity to acrivastine or triprolidine.
- chronic renal failure (creatinine clearance less than 50 mL / min or serum concentrations above 150 umol / L).
- children’s age (12 years)
- pregnancy, lactation
Dosage and administration
Adults and children over 12 years inside, 8 mg (1 capsule) 3 times a day, regardless of the meal, with water.
Drowsiness is rare, sedation comparable to placebo. For the vast majority of patients treated Sempreksom not accompanied by anticholinergic and sedative effects. There have allergic reactions to the development of the rash, and rarely – anaphylactic shock.
Overdose Sempreksom not described.
Upon receipt of up to 1200 mg acrivastine daily symptoms of disorders of the gastrointestinal tract (nausea, vomiting, diarrhea), headache, weakness, drowsiness, absent or poorly developed. Treatment: You can apply gastric lavage if necessary. Symptomatic therapy
Interaction with other medicinal products
The use of acrivastine in combination with alcohol or other drugs, have a depressing winstrol results effect on the central nervous system, may exacerbate this effect.
In applying Sempreksa elderly patients should monitor kidney function.
During treatment, abstain from alcohol.