As well as on the background of combined immunosuppression in general, the appointment of buy winstrolas a component of immunosuppressive schemes have an increased risk of developing lymphomas and other malignancies, particularly of the skin (see. “Side effects”). This risk appears to be associated not with the use of a drug per se, but with the intensity and duration of immunosuppression.
As in all patients with an increased risk of skin cancer, it is necessary to limit exposure to the sun and rays wearing respective closed clothing and using sunscreens creams with a high protection factor.
Patients receiving should be informed of the need to immediately tell your doctor about any signs of infection, bleeding, bleeding or other signs of bone marrow suppression.
Excessive suppression of the immune system can also increase susceptibility to infection, including , opportunistic, sepsis and other infections with a fatal outcome.
During treatment with vaccination may be less effective; you must avoid the use of live attenuated vaccines. It is possible to carry out influenza vaccination in accordance with national guidelines.
Since receiving may be accompanied by adverse reactions from the gastrointestinal tract, caution should be exercised in the appointment of in patients with digestive tract diseases in the acute stage.
Since the is an inhibitor , then, from a theoretical point view, should not be prescribed it to patients with a rare genetically determined hereditary deficiency of hypoxanthine .
MMF is not recommended in conjunction with azathioprine because both drugs inhibit the bone marrow, and their simultaneous reception has not been studied.
caution should be exercised while the appointment with drugs affecting hepatocellular intestinal circulation, as they may reduce the efficacy (see. “drug interactions”).
in patients with severe chronic renal failure should be avoided doses greater than 1 g, 2 times a day.
dose adjustment renal patients with delayed graft function is not required, but they must be carefully monitored. Data on patients who have had a heart transplant or a liver and have severe renal insufficiency, no.
In elderly patients the risk of adverse events may be higher than in younger patients. Laboratory control: it is necessary to determine the complete blood count during treatment with MMF in the first month – weekly, during buy winstrol the second and third months of treatment – two times a month, and then for the first year – a monthly basis. Neutropenia may be associated with a reception MMF or with other drugs, viral infections, or a combination of these reasons. In the event of neutropenia (absolute neutrophil count less than 1300 in 1 mm) is necessary to interrupt treatment or reduce the dose of MMF, with careful monitoring of these patients.
Treatment with the drug
Because mycophenolate mofetil in experiments on rats and rabbits showed teratogenic effects, buy winstrol tablets should not crush and break the integrity o capsules. It is necessary to avoid inhalation of the powder contained in t capsules, or direct contact with skin or mucous membranes. Just water – If this happens, you need to thoroughly wash the site with soap and water, and the eyes.